2. Metabolic Enzyme/Protease
  3. Thrombin
  4. Atecegatran

Atecegatran  (Synonyms: AR-H067637)

目录号: HY-10275
产品使用指南

摩尔计算器

Atecegatran (AR-H067637) 是一种具有口服活性的竞争性 thrombin 抑制剂，Ki 为 2-4 nM。AR-H067637 通过阻断 thrombin 结合到纤维蛋白和 thrombomodulin 来抑制血小板活化与聚集。Atecegatran 在多种血浆凝血检测中展示了显著的抗凝效果，其 IC50 在 93-220 nM。Atecegatran 可用于血疾病领域的研究。

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Atecegatran Chemical Structure

Atecegatran Chemical Structure

CAS No. : 433937-74-7

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Atecegatran 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Atecegatran (AR-H067637) is an orally active competitive thrombin inhibitor with a Ki of 2-4 nM. AR-H067637 inhibits platelet activation and aggregation by blocking thrombin binding to fibrin and thrombomodulin. Atecegatran demonstrates significant anticoagulant effects in various plasma coagulation assays, with an IC50 ranging from 93 to 220 nM. Atecegatran can be used in research related to thromboembolic disorders[1].

分子量

466.87

Formula

C21H21ClF2N4O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Atecegatran 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atecegatran433937-74-7AR-H067637ThrombinInhibitorinhibitorinhibit

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