2. Cell Cycle/DNA Damage PI3K/Akt/mTOR
  3. ATM/ATR
  4. ATR-IN-18

ATR-IN-18 (化合物 2) 是一种口服有效的 ATR 激酶抑制剂，其 IC50 为 0.69 nM。ATR-IN-18 在 LoVo 细胞中显示出抗增殖活性，其 IC50 为 37.34 nM。ATR-IN-18 具有抗肿瘤活性。

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ATR-IN-18 Chemical Structure

ATR-IN-18 Chemical Structure

CAS No. : 2766407-55-8

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ATR-IN-18 相关抗体

Top Publications Citing Use of Products

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ATM ATR

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ATR-IN-18 (compound 2) is an orally active and potent ATR kinase inhibitor, with an IC50 of 0.69 nM. ATR-IN-18 shows antiproliferative activity in LoVo cells, with an IC50 of 37.34 nM. ATR-IN-18 has anti-tumor activity[1].

IC50 & Target

ATR

0.69 nM (IC50)

分子量

517.48

Formula

C19H22F3N7O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ATR-IN-18 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATR-IN-182766407-55-8ATM/ATRAtaxia telangiectasia mutatedATM and RAD3 relatedOCI-LY19 cellanticancer activityLoVo cellsorally activeInhibitorinhibitorinhibit

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产品名称：
ATR-IN-18
目录号：
HY-147570
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