1. Autophagy MAPK/ERK Pathway Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  2. Autophagy JNK Reactive Oxygen Species
  3. Autophagy inducer 5

Autophagy inducer 5 (compound 21o) 是有效的 MCF-7 抑制剂 (IC50: 2 μM),和潜在的乳腺癌抑制剂。Autophagy inducer 5 通过激活 ROS/JNK 信号通路来诱导细胞自噬,可增加 ROS 生成和 JNK 磷酸化,发挥细胞毒性作用。

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Autophagy inducer 5 Chemical Structure

Autophagy inducer 5 Chemical Structure

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  • 生物活性

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生物活性

Autophagy inducer 5 (compound 21o) is a potent MCF-7 inhibitor (IC50: 2 μM), and a potential breast cancer inhibitor. Autophagy inducer 5 induces cellular autophagy by activating the ROS/JNK signaling pathway, which increases ROS generation and JNK phosphorylation, exerting cytotoxic effects[1].

分子量

648.88

Formula

C41H52N4O3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Autophagy inducer 5
目录号:
HY-159605
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