2. Apoptosis Immunology/Inflammation
  3. Pyroptosis
  4. Azalamellarin N

Azalamellarin N  (Synonyms: AZL-N)

目录号: HY-162150 纯度: 99.58%
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Azalamellarin N 是细胞焦亡 (Pyroptosis) 的抑制剂，对不同焦亡诱导剂的抑制效力不同。Azalamellarin N 通过靶向作用于 NLRP3 炎症小体激活上游的分子来抑制细胞焦亡 (Pyroptosis)，而不是直接靶向 NLRP3 炎症小体的成分。对不同焦亡 (Pyroptosis) 诱导剂的抑制效力：Nigericin (HY-127019) >R837 (HY-B0180)。

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Azalamellarin N Chemical Structure

Azalamellarin N Chemical Structure

CAS No. : 1809535-57-6

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1 mg ￥7000
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Azalamellarin N 相关抗体

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生物活性

Azalamellarin N is an inhibitor of pyroptosis and has different inhibitory effects on different pyroptosis inducers. Azalamellarin N inhibits pyroptosis by targeting molecules that act upstream of NLRP3 inflammasome activation, rather than directly targeting components of the NLRP3 inflammasome. Inhibitory potency against different pyroptosis inducers: Nigericin (HY-127019) > R837 (HY-B0180)[1].

分子量

498.48

Formula

C28H22N2O7
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Azalamellarin N 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Azalamellarin N1809535-57-6AZL-NPyroptosisPyroptosis inhibitioninflammasomeinflammasome assemblyNLRP3Inhibitorinhibitorinhibit

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