1. GPCR/G Protein
  2. GnRH Receptor
  3. Azaline

Azaline (Azaline A) 是一种促性腺激素释放激素 (GnRH) 受体拮抗剂,KD 值为 0.48 nM。Azaline 能够有效地诱导组胺释放,其效果与 GnRH 相当,可在每只雌性大鼠 2.0-3.0 μg 的剂量下完全抑制其排卵。Azaline 在调节生殖功能方面具有潜在的应用价值。

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Azaline Chemical Structure

Azaline Chemical Structure

CAS No. : 134457-26-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Azaline (Azaline A) is a gonadotropin-releasing hormone (GnRH) receptor antagonist with a KD value of 0.48 nM. Azaline can effectively induce histamine release, with an effect comparable to that of GnRH, and it can completely inhibit ovulation at a dose of 2.0-3.0 μg per female rat. Azaline has potential applications in regulating reproductive functions[1].

分子量

1545.23

Formula

C74H106ClN23O12

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Azaline
目录号:
HY-P3317
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