2. Neuronal Signaling
  3. Amyloid-β
  4. Azeliragon dihydrochloride

Azeliragon dihydrochloride  (Synonyms: TTP488 dihydrochloride; PF-04494700 dihydrochloride)

目录号: HY-50682A
产品使用指南

摩尔计算器

Azeliragon dihydrochloride (TTP488) 是一种生物可利用的晚期糖基化终产物 (RAGE) 受体抑制剂，可缓解轻度阿尔茨海默病 (AD) 的发展。Azeliragon dihydrochloride 还可穿过血脑屏障 (BBB)。

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Azeliragon dihydrochloride Chemical Structure

Azeliragon dihydrochloride Chemical Structure

CAS No. : 1284150-65-7

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Azeliragon dihydrochloride 的其他形式现货产品:

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Azeliragon dihydrochloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Azeliragon dihydrochloride (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression in patients with mild Alzheimer’s disease (AD)[1]. Azeliragon dihydrochloride also can cross the blood-brain barrier (BBB)[2].

分子量

605.04

Formula

C32H40Cl3N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Azeliragon dihydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Azeliragon1284150-65-7TTP488PF-04494700TTP 488TTP-488PF04494700PF 04494700Amyloid-ββ-amyloid peptideAβAbetaInhibitorinhibitorinhibit

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目录号：
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