1. GPCR/G Protein
  2. Bradykinin Receptor
  3. B4148

B4148 是一种选择性竞争性缓激肽 (BK) 拮抗剂,可显著抑制大鼠中 BK 诱发的低血压。在由大肠杆菌脂多糖诱发的内毒素休克大鼠模型中,与对照组相比,B4148 显著缓解了平均动脉血压的下降。

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Custom Peptide Synthesis

B4148 Chemical Structure

B4148 Chemical Structure

CAS No. : 103412-37-9

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查看 Bradykinin Receptor 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

B4148 is a selective competitive bradykinin (BK) antagonist that significantly inhibits BK-induced hypotension in rats. In a rat model of endotoxin shock induced by Escherichia coli lipopolysaccharide, B4148 significantly attenuated the decrease in mean arterial blood pressure compared with the control group[1].

分子量

1394.67

Formula

C62H95N19O14S2

CAS 号
Sequence

Lys-Lys-Arg-{Hyp}-Pro-Gly-{Thi}-Ser-Phe-{Thi}-Arg

Sequence Shortening

KKR-{Hyp}-PG-{Thi}-SF-{Thi}-R

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
B4148
目录号:
HY-P1694
需求量: