2. GPCR/G Protein
  3. Leukotriene Receptor
  4. BayCysLT2

BayCysLT2，间苯二甲酸衍生物，是一种选择性强效的半胱氨酸白三烯2 (CysLT2) 受体拮抗剂，IC50 值为 53 nM。BayCysLT2 抑制白三烯 D4 在表达人 CysLT2 受体的 HEK293 细胞中诱导的钙动员。BayCysLT2 逆转 LTC4 诱导的离体灌注豚鼠心脏冠脉灌注压升高和收缩力降低。

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BayCysLT2 Chemical Structure

BayCysLT2 Chemical Structure

CAS No. : 712313-33-2

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BayCysLT2 相关抗体

Top Publications Citing Use of Products

查看 Leukotriene Receptor 亚型特异性产品:

查看所有亚型
LTB4 LTC4/CysLT2 LTD4/CysLT1 LTE4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BayCysLT2, an isophthalic acid derivative, is a selective and potent cysteinyl leukotriene 2 (CysLT2) receptor antagonist with an IC50 value of 53 nM. BayCysLT2 inhibits calcium mobilization induced by leukotriene D4 in HEK293 cells expressing human CysLT2 receptors. BayCysLT2 reverses LTC4-induced increases in coronary artery perfusion pressure and decreases in contractility in isolated perfused guinea pig hearts[1][2].

分子量

589.68

Formula

C34H39NO8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BayCysLT2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BayCysLT2712313-33-2BayCysLT 2BayCysLT-2Leukotriene ReceptorCysLT2 receptorcalcium mobilizationleukotriene D4HEK293 cellsguinea pigInhibitorinhibitorinhibit

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目录号：
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