1. Apoptosis
  2. Bcl-2 Family
  3. Bcl-2/Mcl-1-IN-1

Bcl-2/Mcl-1-IN-1 (化合物 3) 是一种 Bcl-2/Mcl-1 抑制剂,对 Mcl-1Bcl-2Ki 值分别为 1.19 μM 和 4.53 μM。Bcl-2/Mcl-1-IN-1 可用于癌症研究。

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Bcl-2/Mcl-1-IN-1 Chemical Structure

Bcl-2/Mcl-1-IN-1 Chemical Structure

CAS No. : 2673361-08-3

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查看 Bcl-2 Family 亚型特异性产品:

  • 生物活性

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生物活性

Bcl-2/Mcl-1-IN-1 (compound 3) is a Bcl-2/Mcl-1 inhibitor, with Kis of 1.19 μM and 4.53 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-1 can be used for the research of cancer[1].

IC50 & Target[1]

Mcl-1

1.19 μM (Ki)

Bcl-2

4.53 μM (Ki)

分子量

421.49

Formula

C28H23NO3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Bcl-2/Mcl-1-IN-1
目录号:
HY-144430
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