1. GPCR/G Protein Neuronal Signaling
  2. Opioid Receptor
  3. β-Endorphin, equine TFA

β-Endorphin, equine TFA 

目录号: HY-P1866A 纯度: 97.32%
COA 产品使用指南

β-Endorphin, equine TFA 是一种内源性阿片类多肽,对 μ 和 δ 阿片受体 (μ/δ opioid receptors) 有很强的亲和性。β-Endorphin, equine TFA 具有止痛作用。

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Custom Peptide Synthesis

β-Endorphin, equine TFA Chemical Structure

β-Endorphin, equine TFA Chemical Structure

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
500 μg ¥900
In-stock
1 mg ¥1500
In-stock
5 mg ¥3500
In-stock
10 mg ¥6000
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Other Forms of β-Endorphin, equine TFA:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

β-Endorphin, equine TFA is an endogenous opioid peptide, which binds at high affinity to both μ/δ opioid receptors. β-Endorphin, equine TFA has analgesic properties[1][2][3][4].

IC50 & Target

δ Opioid Receptor/DOR

 

μ Opioid Receptor/MOR

 

体外研究
(In Vitro)

β-Endorphin, equine TFA (0, 0.6, 1.2 和 3 μM) 抑制纹状体多巴胺释放[4]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

β-Endorphin, equine TFA (2 或 20 μg/kg;腹腔注射,一次) 影响大鼠的习得和保留。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult Female Wistar rats[3]
Dosage: 2 or 20 μg/kg
Administration: 2 or 20 μg/kg; i.p., once
Result: Hindered the acquisition of shuttle avoidance learning and habituation of a rearing response to a tone at a dose of 20 μg/kg. Caused amnesia in the avoidance task with the pre- or post-training administration of 2 μg/kg and pre-training administration of 20 μg/kg.
分子量

3423.94 (free acid)

Formula

C154H248N42O44S.xC2HF3O2

性状

固体

颜色

White to off-white

Sequence

Tyr-Gly-Gly-Phe-Met-Ser-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-His-Lys-Lys-Gly-Gln

Sequence Shortening

YGGFMSSEKSQTPLVTLFKNAIIKNAHKKGQ

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验: 

H2O 中的溶解度 : 100 mg/mL (超声助溶)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳,请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度,如有需要,请与 MCE 中国技术支持联系。
纯度 & 产品资料
参考文献
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
β-Endorphin, equine TFA
目录号:
HY-P1866A
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