2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. Bimatoprost acid

Bimatoprost acid  (Synonyms: 17-Phenyl trinor PGF2α)

目录号: HY-125774
产品使用指南

摩尔计算器

Bimatoprost acid (17-Phenyl trinor PGF2α) ，Bimatoprost (HY-B0191) 的酸水解产物，是一种强效的前列腺素 FP 受体激动剂。

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Bimatoprost acid Chemical Structure

Bimatoprost acid Chemical Structure

CAS No. : 38344-08-0

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规格 价格 是否有货
1 mg ￥1650
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Other Forms of Bimatoprost acid:

Bimatoprost acid 相关抗体

Top Publications Citing Use of Products

查看 Prostaglandin Receptor 亚型特异性产品:

查看所有亚型
DP EP FP IP TXA2/TP TXB2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bimatoprost acid (17-Phenyl trinor PGF2α), the acid hydrolysis product of Bimatoprost (HY-B0191), is a potent agonist of prostaglandin FP receptor[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CHO EC50
> 10000 nM
Compound: 1
Agonist activity at human IP receptor expressed in CHO cells assessed as increase in intracellular cAMP level by HTRF method
Agonist activity at human IP receptor expressed in CHO cells assessed as increase in intracellular cAMP level by HTRF method
[PMID: 28105284]
CHO EC50
12 nM
Compound: 1
Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay
Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay
[PMID: 28105284]
CHO EC50
8600 nM
Compound: 1
Agonist activity at human EP3 receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay
Agonist activity at human EP3 receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based fluorescence assay
[PMID: 28105284]
分子量

388.50

Formula

C23H32O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Bimatoprost acid 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bimatoprost acid38344-08-017-Phenyl trinor PGF2αProstaglandin ReceptorBimatoprostglaucomaInhibitorinhibitorinhibit

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