1. Biology Dictionary
  2. Enzymatic Footprint Analysis

Enzymatic Footprint Analysis酶足迹分析

释义:

Binding sites are identified by altered reactivity of a complex to an enzymatic probe compared to the unbound molecules. Residues in close contact with the binding partner are protected from cleavage by the enzyme. When these enzymes are administrated to intact cells, the pattern of protection from the probes identifies the location of DNA-protein or protein-protein interactions in vivo.

通过与酶探针的反应性变化,识别结合位点,这些变化表明复合物与未结合分子的反应性不同。与结合伙伴密切接触的残基被保护免受酶的裂解。当这些酶被施加到完整的细胞时,来自探针的保护模式识别 DNA-蛋白质或蛋白质-蛋白质相互作用在体内的位置。

MCE 生物医学词典

MCE 生物医学词典是全面和专业的生物学术专有名词和主题数据合集。在这里您可以搜索到您想了解的专业名词的准确解释,并且所有名词解释均有权威书籍或者高影响因子文献的支持。
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #