2. Immunology/Inflammation Apoptosis
  3. CD73 Apoptosis
  4. BK50164

BK50164 是一种有效的 CD73 抑制剂，IC50 值为 13.089 µM。BK50164 与 CD99 结合 KD 值为 1.5 µM。BK50164 显示抗增殖活性。BK50164 诱导细胞凋亡 (Apoptosis) 和细胞周期停滞在 Sub-G1 阶段。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

我们将采用定制合成服务的方式为您快速提供所需产品和技术服务

BK50164 Chemical Structure

BK50164 Chemical Structure

CAS No. : 2204291-78-9

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

BK50164 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 µM. BK50164 binds to CD99 with a KD value of 1.5 µM. BK50164 shows antiproliferative activity. BK50164 induced Apoptosis and cell cycle arrest at Sub-G1 phase[1].

IC50 & Target

IC50: 13.089 µM (CD73)[1]
体外研究
(In Vitro)

BK50164 (0-400 µM；48 小时) 显示抗增殖活性，对 A4573, TC-32, TC-71, Saos-2, U-2 OS 细胞的 IC50 值分别为35.8, 34.28, 5.17, ≥400, ≥400 µM[2]。
BK50164 (4-16 µM; 48 h) 诱导细胞凋亡和细胞周期停滞在 Sub-G1 期[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

BK50164 相关抗体:

Cell Viability Assay[2]

Cell Line: A4573, TC-32, TC-71, Saos-2, U-2 OS cells
Concentration: 0-400 µM
Incubation Time: 48 h
Result: Inhibited cell viability witn IC50s of 35.8, 34.28, 5.17, ≥400, ≥400 µM for A4573, TC-32, TC-71, Saos-2, U-2 OS cells, respectively.

Cell Cycle Analysis[2]

Cell Line: TC-32, U-2 OS cells
Concentration: 4, 8, 16 µM
Incubation Time: 48 h
Result: Induced apoptosis in only TC-32 ES cells but not in U-2 OS cell line and induces cell cycle arrest at Sub-G1 phase.
分子量

405.72

Formula

C13H13ClFN5O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BK50164 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BK501642204291-78-9BK 50164BK-50164CD73Apoptosisecto-5′-nucleotidase, NT5ETC-32U-2 OS cellsantiproliferativeapoptosisSub-G1 phaseInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
BK50164
目录号：
HY-150048
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z