2. Cell Cycle/DNA Damage Cytoskeleton
  3. Microtubule/Tubulin
  4. Blestriarene B

Blestriarene B  (Synonyms: (-)-Blestriarene B)

目录号: HY-142013
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Blestriarene B ((-)-Blestriarene B) 是一种利用微管蛋白聚合抑制作用从白芨 (兰科) 中分离得到的二苯乙烯类化合物。

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Blestriarene B Chemical Structure

Blestriarene B Chemical Structure

CAS No. : 127211-03-4

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Blestriarene B 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Blestriarene B ((-)-Blestriarene B) a stilbenoid isolated by the guidance of inhibitory effect of tubulin polymerization from the tubers of Bletilla striata (Orchidaceae)[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 EC50
11.2 μM
Compound: Cirrhopetalanthrin
Cytotoxicity against human A549 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human A549 cells after 3 days by sulforhodamine B assay
[PMID: 19193043]
BV-2 IC50
46.8 μM
Compound: 22
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess assay
Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess assay
[PMID: 31415170]
HCT-8 EC50
7.3 μM
Compound: Cirrhopetalanthrin
Cytotoxicity against human HCT8 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human HCT8 cells after 3 days by sulforhodamine B assay
[PMID: 19193043]
MCF7 EC50
12.5 μM
Compound: Cirrhopetalanthrin
Cytotoxicity against human MCF7 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human MCF7 cells after 3 days by sulforhodamine B assay
[PMID: 19193043]
Neutrophil IC50
0.6 μM
Compound: 28
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
[PMID: 27525452]
Neutrophil IC50
0.9 μM
Compound: 28
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
[PMID: 27525452]
分子量

480.51

Formula

C30H24O6
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Blestriarene B 相关分类

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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Blestriarene B127211-03-4(-)-Blestriarene BMicrotubule/TubulinstilbenoidBletilla striataInhibitorinhibitorinhibit

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