2. Protein Tyrosine Kinase/RTK
  3. Btk
  4. BLK-IN-1

BLK-IN-1 (compound 1) 是一种选择性的共价的 B-淋巴酪氨酸激酶 (BLK) 和 BTK 抑制剂，IC50 值分别为 18.8 nM 和 20.5 nM。BLK-IN-1 可用于癌症研究。

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BLK-IN-1 Chemical Structure

BLK-IN-1 Chemical Structure

CAS No. : 1431727-00-2

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BLK-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BLK-IN-1 (compound 1) is a selective and covalent inhibitor of B-Lymphoid tyrosine kinase (BLK) and BTK, with IC50s of 18.8 nM and 20.5 nM, respectively. BLK-IN-1 can be used for the research of cancer[1].

IC50 & Target

IC50: 18.8 nM (BLK), 20.5 nM (BTK)[1]
分子量

560.53

Formula

C29H23F3N6O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BLK-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BLK-IN-11431727-00-2BtkBruton tyrosine kinaseB-Lymphoid tyrosine kinaseBLKcancerInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-144283
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