2. GPCR/G Protein
  3. CRFR
  4. BMS-665053

BMS-665053 是一种促肾上腺皮质激素释放因子 1 (CRF1) 受体拮抗剂 (IC50 = 1.0 nM)。 BMS-665053)11 是人 Y-79 视网膜母细胞瘤细胞中 CRF 刺激的环磷酸腺苷 (cAMP) 产生的有效抑制剂 (IC50 = 4.9 nM)[1]。

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BMS-665053 Chemical Structure

BMS-665053 Chemical Structure

CAS No. : 1173435-64-7

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BMS-665053 相关抗体

Top Publications Citing Use of Products

查看 CRFR 亚型特异性产品:

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CRFR1 CRFR2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BMS-665053 is a corticotropin-releasing factor-1 (CRF1) receptor antagonist (IC50 = 1.0 nM). BMS-665053)11 is a potent inhibitor of CRF-stimulated cyclic adenosine monophosphate (cAMP) production in human Y-79 retinoblastoma cells (IC50 = 4.9 nM)[1].

分子量

424.66

Formula

C16H14Cl3F2N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BMS-665053 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMS-6650531173435-64-7BMS665053BMS 665053CRFRCorticotropin-releasing Factor ReceptorCRHRcorticotropin-releasing factor-1 (CRF1) receptorCRF-stimulated cyclic adenosine monophosphate (cAMP)Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-14132
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