2. Signaling Pathways
  3. GPCR/G Protein
  4. CRFR
  5. CRFR Inhibitors

CRFR Inhibitors

CRFR1

CRFR2

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

CRFR Inhibitors, Agonists, Antagonists & Modulators
Product Name CRFR1 CRFR2 Purity
R121919
CRFR1, Ki: 2-5 nM
  99.53%
Cortagine
CRFR1
  99.53%
CP 376395
CRFR1
CRFR2
99.68%
Urocortin, rat
CRFR1
CRFR2
Tildacerfont
CRFR1
  98.25%
Urocortin II, human  
CRFR2
α-Helical CRF(9-41) TFA
CRFR1
CRFR2
99.72%
R121919 hydrochloride
CRFR1, Ki: 2-5 nM
 
Urocortin II, mouse
CRFR1, Ki: ﹥100 nM
CRFR2, Ki: 0.66 nM
K41498  
CRFR2
Urocortin II, human TFA  
CRFR2
NBI 35965 methanesulfonate
CRFR1, Ki: 4 nM
CRFR1, pKi: 8.5
 
NBI 35965 hydrochloride
CRFR1, Ki: 4 nM
CRFR1, pKi: 8.5
 
CP 376395 hydrochloride
CRFR1
CRFR2
(Tyr0)-Urocortin, rat
CRFR1
CRFR2
NBI-35965
CRFR1
 
NBI-34041
CRFR1, IC50: 58.9 nM
CRFR1, Ki: 4 nM
CRFR2, IC50: >10000 nM
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