2. Others Apoptosis
  3. Fluorescent Dye Ferroptosis
  4. BODIQPy-TPA

BODIQPy-TPA 是一种亲脂性探针，在光照射下通过脂质过氧化诱导 B16 和 HepG2 细胞铁死 (ferroptosis)。 BODIQPy-TPA 的最大吸收波长为 488 nm，最大发射波长超过 640 nm。

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BODIQPy-TPA Chemical Structure

BODIQPy-TPA Chemical Structure

CAS No. : 2738333-02-1

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BODIQPy-TPA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BODIQPy-TPA is a lipophilic probes, which induces ferroptosis in B16 and HepG2 cells upon light irradiation through lipid peroxidation. BODIQPy-TPA reveals a maximum absorption wavelength of 488 nm and a maximum emission wavelength above 640 nm[1].

体外研究
(In Vitro)

BODIQPy-TPA (5 μM) ferrostatin 依赖性的在蓝光 LED 照射下的 B16 细胞中显示光毒性，IC50 为 0.51 μM，并且下调 ferritin heavy polypeptide 1 (FTH1) 的表达[1]。
BODIQPy-TPA (5 μM) 通过光照射增加三酰甘油 (TG) 水平，下调磷脂酰胆碱 (PC) 的水平[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

BODIQPy-TPA 相关抗体:

Cell Viability Assay[1]

Cell Line: B16
Concentration: 0-50 μM
Incubation Time: 48 h
Result: Inhibited B16 cells viability, decreased the cytotoxicity with presence of ferrostatin.

Western Blot Analysis[1]

Cell Line: B16
Concentration: 5 μM
Incubation Time: 48 h
Result: Decreased levels of FTH1.
分子量

540.37

Formula

C33H23BF2N4O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BODIQPy-TPA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BODIQPy-TPA2738333-02-1Fluorescent DyeFerroptosisFerrostatinB16HepG2ferroptosisphotocytotoxicperoxidationInhibitorinhibitorinhibit

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