2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. BPIC

BPIC 是一种 DNA 嵌入剂，也是一种抗癌剂。BPIC 可清除 ∙OH、∙O2(-) 和 NO 自由基。

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BPIC Chemical Structure

BPIC Chemical Structure

CAS No. : 1444382-92-6

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BPIC 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BPIC is a DNA intercalator agent and also an anti-cancer agent. BPIC scavenge ∙OH, ∙O2(-), and NO free radicals[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
CCRF S-180 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against mouse S180 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
HeLa IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
HepG2 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
HL-60 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
HT-29 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
K562 IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human K562 cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
SH-SY5Y IC50
0.96 μM
Compound: BPIC
Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay
Antiproliferative activity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay
[PMID: 25648297]
分子量

452.46

Formula

C27H20N2O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BPIC 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BPIC1444382-92-6DNA/RNA SynthesisDNA intercalatorfree radicalInhibitorinhibitorinhibit

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产品名称：
BPIC
目录号：
HY-117457
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