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  3. Brequinar sodium

Brequinar sodium  (Synonyms: 布喹那钠盐; DuP785 sodium; NSC 368390 sodium)

目录号: HY-108325A
产品使用指南

Brequinar (sodium) 是一种生化试剂,可作为生物材料或有机化合物,用于生命科学相关研究。

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Brequinar sodium Chemical Structure

Brequinar sodium Chemical Structure

CAS No. : 96201-88-6

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规格 是否有货
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100 mg   询价  
250 mg   询价  

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Brequinar sodium 的其他形式现货产品:

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Other Forms of Brequinar sodium:

  • 生物活性

  • 纯度 & 产品资料

生物活性

Brequinar (sodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A-375 IC50
8.1 μM
Compound: Breq
Antiproliferative activity against human A375 cells for 24 hrs by MTT assay
Antiproliferative activity against human A375 cells for 24 hrs by MTT assay
[PMID: 24929289]
BXPC-3 IC50
0.94 μM
Compound: Brequinar Sodium
Cytotoxicity against human BxPC3 cells assessed as decrease in cell proliferation after 72 hrs by MTT reduction assay
Cytotoxicity against human BxPC3 cells assessed as decrease in cell proliferation after 72 hrs by MTT reduction assay
10.1039/C6MD00179C
HCT-116 IC50
0.158 μM
Compound: Brequinar Sodium
Cytotoxicity against human HCT116 cells assessed as decrease in cell proliferation after 72 hrs by MTT reduction assay
Cytotoxicity against human HCT116 cells assessed as decrease in cell proliferation after 72 hrs by MTT reduction assay
10.1039/C6MD00179C
Hep 3B2 IC50
10.22 μM
Compound: Breq
Antiproliferative activity against human Hep3B cells for 24 hrs by MTT assay
Antiproliferative activity against human Hep3B cells for 24 hrs by MTT assay
[PMID: 24929289]
HT-29 IC50
13.98 μM
Compound: Brequinar sodium
Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
[PMID: 30738663]
MDA-MB-231 IC50
12.45 μM
Compound: Brequinar sodium
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
[PMID: 30738663]
WI-38 IC50
33.954 μM
Compound: Brequinar Sodium
Cytotoxicity against human WI38 cells assessed as decrease in cell proliferation after 72 hrs by MTT reduction assay
Cytotoxicity against human WI38 cells assessed as decrease in cell proliferation after 72 hrs by MTT reduction assay
10.1039/C6MD00179C
体外研究
(In Vitro)

强效选择性 DHODH 抑制剂

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
分子量

397.35

Formula

C23H14F2NNaO2

CAS 号
中文名称

布喹那钠盐;DuP785钠盐; NSC 368390钠盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Brequinar sodium
目录号:
HY-108325A
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