2. PROTAC
  3. PROTAC Linkers
  4. Brigatinib C

Brigatinib C 是 HJM-561 (HY-156698) 组装为 PROTAC 的 Linker 部分。

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Brigatinib C Chemical Structure

Brigatinib C Chemical Structure

CAS No. : 1197958-75-0

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Customer Review

Brigatinib C 相关抗体

Top Publications Citing Use of Products

查看 PROTAC Linkers 亚型特异性产品:

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

  • 生物活性

  • 纯度 & 产品资料

生物活性

Brigatinib C is a linker, as a part of PROTAC Linker to target HJM-561 (HY-156698).

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
SR IC50
6.8 nM
Compound: Brigatinib C
Antiproliferative activity against human SR cells assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay
Antiproliferative activity against human SR cells assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay
[PMID: 34138566]
分子量

570.07

Formula

C28H37ClN7O2P
CAS 号
性状

固体

颜色

Off-white to light brown

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

Brigatinib C 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Brigatinib C1197958-75-0PROTAC LinkersInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-150910
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