1. Metabolic Enzyme/Protease
  2. Angiotensin-converting Enzyme (ACE)
  3. Captopril hydrochloride

Captopril hydrochloride  (Synonyms: SQ 14225 hydrochloride)

目录号: HY-B0368A
产品使用指南

Captopril (SQ 14225) hydrochloride 是一种含巯基的口服活性血管紧张素转换酶 (ACE) 抑制剂 (IC50=0.025 μM),广泛应用于高血压和充血性心力衰竭的研究。Captopril hydrochloride 也是 NDM-1 抑制剂,IC50 值为 7.9 μM。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Captopril hydrochloride Chemical Structure

Captopril hydrochloride Chemical Structure

CAS No. : 198342-23-3

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Captopril hydrochloride 的其他形式现货产品:

Customer Review

Other Forms of Captopril hydrochloride:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Captopril (SQ 14225) hydrochloride, antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) and has been widely used for research of hypertension and congestive heart failure. Captopril hydrochloride is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 7.9 μM[1][2][3].

IC50 & Target

ACE[1]

体外研究
(In Vitro)

Captopril (SQ 14225) hydrochloride has been shown to have similar morbidity and mortality benefits to those of diuretics and beta-blockers in hypertensive patients. Captopril hydrochloride has been shown to delay the progression of diabetic nephropathy, and enalapril and lisinopril prevent the development of nephropathy in normoalbuminuric patients with diabetes[4].
An equimolar ratio of the cis and trans states of Captopril hydrochloride exists in solution and that the enzyme selects only the trans state of the inhibitor that presents architectural and stereoelectronic complementarity with its substrate binding groove[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
分子量

253.75

Formula

C9H16ClNO3S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Captopril hydrochloride
目录号:
HY-B0368A
需求量: