2. Anti-infection Apoptosis Autophagy NF-κB Metabolic Enzyme/Protease Immunology/Inflammation
  3. Bacterial Apoptosis Antibiotic Parasite Autophagy Reactive Oxygen Species
  4. 622-78-6

622-78-6

Benzyl isothiocyanate Chemical Structure

Chemical Structure

622-78-6

  • Benzyl isothiocyanate
  • Synonym(s)： 苄基异硫氰酸酯
  • CAS No.：622-78-6
  • Formula：C8H7NS
  • Molecular Weight：149.21

生物活性：Benzyl isothiocyanate 是一种口服有效的异硫氰酸酯，具有杀菌、抗癌、抗血管生成和驱虫活性。Benzyl isothiocyanate 通过调节细胞凋亡 (apoptosis)、细胞增殖、细胞周期阻滞、转移、血管生成、自噬 (autophagy) 等多种信号通路发挥抗癌功能。此外，Benzyl isothiocyanate 可以增强肌肉的胰岛素敏感性来改善肥胖引起的高血糖。

Benzyl isothiocyanate is an orally available isothiocyanate with bactericidal, anticancer, antiangiogenic and anthelmintic activities. Benzyl isothiocyanate exerts anticancer functions by regulating multiple signaling pathways, including apoptosis, cell proliferation, cell cycle arrest, metastasis, angiogenesis, and autophagy. In addition, Benzyl isothiocyanate can enhance muscle insulin sensitivity to improve obesity-induced hyperglycemia[1][2][3][4][5][6][7][8][9].

Cat. No. 产品名称 纯度 描述 价格
HY-77813R Benzyl isothiocyanate (Standard) ≥98% Benzyl isothiocyanate (Standard)是 Benzyl isothiocyanate 的分析标准品。本产品用于研究及分析应用。Benzyl isothiocyanate 是一种口服有效的异硫氰酸酯，具有杀菌、抗癌、抗血管生成和驱虫活性。Benzyl isothiocyanate 通过调节细胞凋亡 (apoptosis)、细胞增殖、细胞周期阻滞、转移、血管生成、自噬 (autophagy) 等多种信号通路发挥抗癌功能。此外，Benzyl isothioc
HY-77813 Benzyl isothiocyanate 99.62% Benzyl isothiocyanate 是一种口服有效的异硫氰酸酯，具有杀菌、抗癌、抗血管生成和驱虫活性。Benzyl isothiocyanate 通过调节细胞凋亡 (apoptosis)、细胞增殖、细胞周期阻滞、转移、血管生成、自噬 (autophagy) 等多种信号通路发挥抗癌功能。此外，Benzyl isothiocyanate 可以增强肌肉的胰岛素敏感性来改善肥胖引起的高血糖。

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规格 价格 是否有货 数量 操作
10 mM * 1mL

￥550.00

 In-stock
100 mg

￥500.00

 In-stock
HY-77813S Benzyl isothiocyanate-d7 Benzyl isothiocyanate-d7 是 Benzyl isothiocyanate 的氘代物。Benzyl isothiocyanate 是一种天然异硫氰酸酯，具有杀菌活性。Benzyl isothiocyanate 能有效抑制小鼠黑色素瘤细胞的迁移、迁移和侵袭性及 MMP-2 活性。

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规格 价格 是否有货 数量 操作
5 mg
50 mg

References

[1]. Abdel-Kader MS, et al. Quantitative Analysis of Benzyl Isothiocyanate in Salvadora persica Extract and Dental Care Herbal Formulations Using Reversed Phase C18 High-Performance Liquid Chromatography Method. Pharmacogn Mag. 2017 Oct;13(Suppl 3):S412-S416. [Content Brief]
[2]. Lai KC, et al. Benzyl isothiocyanate and phenethyl isothiocyanate inhibit murine melanoma B16F10 cell migration and invasion in vitro. Int J Oncol. 2017 Sep;51(3):832-840. [Content Brief]
[3]. Dinh T N, et al. Anticancer activities of dietary benzyl isothiocyanate: A comprehensive review[J]. Pharmacological Research, 2021, 169: 105666. [Content Brief]
[4]. Kassie F, et al. Genotoxic effects of benzyl isothiocyanate, a natural chemopreventive agent[J]. Mutagenesis, 1999, 14(6): 595-604. [Content Brief]
[5]. Kermanshai R, et al. Benzyl isothiocyanate is the chief or sole anthelmintic in papaya seed extracts[J]. Phytochemistry, 2001, 57(3): 427-435. [Content Brief]
[6]. Jensen J, et al. The toxic effects of benzyl glucosinolate and its hydrolysis product, the biofumigant benzyl isothiocyanate, to Folsomia fimetaria[J]. Environmental Toxicology and Chemistry, 2010, 29(2): 359-364. [Content Brief]
[7]. Pintão A M, et al. In vitro and in vivo antitumor activity of benzyl isothiocyanate: a natural product from Tropaeolum majus[J]. Planta Medica, 1995, 61(03): 233-236. [Content Brief]
[8]. Chuang W T, et al. Benzyl isothiocyanate ameliorates high-fat diet-induced hyperglycemia by enhancing Nrf2-dependent antioxidant defense-mediated IRS-1/AKT/TBC1D1 signaling and GLUT4 expression in skeletal muscle[J]. Journal of agricultural and food chemistry, 2020, 68(51): 15228-15238. [Content Brief]
[9]. Dinh T N, et al. Anticancer activities of dietary benzyl isothiocyanate: A comprehensive review[J]. Pharmacological Research, 2021, 169: 105666.

Keywords:

Benzyl isothiocyanate (Standard)Benzyl isothiocyanateBenzyl isothiocyanate-d7

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