1. Metabolic Enzyme/Protease NF-κB Immunology/Inflammation
  2. Xanthine Oxidase Reactive Oxygen Species
  3. CC15009

CC15009 是一种黄嘌呤氧化还原酶 (XOR) 抑制剂,IC50 值为 0.237 nM。CC15009 可以抑制 XOR 的氧化亚型,从而减少副产物 ROS 的产生,具有抗氧化活性。CC15009 在两种不同的 XOR 底物诱导的高尿酸血症小鼠模型中显示出良好的剂量依赖性尿酸降低作用。

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CC15009 Chemical Structure

CC15009 Chemical Structure

CAS No. : 2482713-67-5

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  • 生物活性

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生物活性

CC15009 is a xanthine oxidoreductase (XOR) inhibitor, with an IC50 value of 0.237 nM. CC15009 can inhibit the oxidative subtype of XOR, thereby reducing the production of the byproduct ROS and exhibiting antioxidant activity. CC15009 has demonstrated a good dose-dependent uric acid-lowering effect in two different mouse models of hyperuricemia induced by XOR substrates[1].

分子量

434.32

Formula

C20H21Cl2N5O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CC15009
目录号:
HY-162882
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