1. Cell Cycle/DNA Damage MAPK/ERK Pathway
  2. DNA/RNA Synthesis Raf
  3. CCT239065

CCT239065 是一种可口服的突变蛋白激酶 V600EBRAF (RAF) 的有效抑制剂,具有抗肿瘤活性。CCT239065 在癌细胞中抑制 V600EBRAF 下游信号,阻断 DNA合成,抑制增殖。

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CCT239065 Chemical Structure

CCT239065 Chemical Structure

CAS No. : 1163719-51-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CCT239065 is an orally available, effective inhibitor of the mutant protein kinase V600EBRAF (RAF) with anti-tumor activity. CCT239065 inhibits downstream signaling of V600EBRAF in cancer cells, blocking DNA synthesis and suppressing proliferation[1][2].

分子量

555.65

Formula

C29H29N7O3S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CCT239065
目录号:
HY-14716
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