2. GPCR/G Protein
  3. PTHR
  4. CH5447240

CH5447240 是甲状旁腺激素受体 1 (PTHR1) 的激动剂，可抑制人 PTHR1，EC50 为 12 μM。CH5447240 在人类肝微粒体中表现出良好的代谢稳定性。CH5447240 可提高大鼠血清钙水平。CH5447240 可用于甲状旁腺功能减退的研究。

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CH5447240 Chemical Structure

CH5447240 Chemical Structure

CAS No. : 1253919-92-4

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CH5447240 相关抗体

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PTH1R

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CH5447240 is an agonist for parathyroid hormone receptor 1 (PTHR1), that inhibits human PTHR1 with an EC50 of 12 μM. CH5447240 exhibits good metabolic stability in human liver microsomes. CH5447240 increases serum calcium levels in rats. CH5447240 can be used in research about hypoparathyroidism[1].

IC50 & Target

PTH1R

12 μM (EC50)

分子量

517.68

Formula

C26H39N5O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CH5447240 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CH54472401253919-92-4CH 5447240CH-5447240PTHRParathyroid hormone receptorHypoparathyroidismSprague Dawley ratInhibitorinhibitorinhibit

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产品名称：
CH5447240
目录号：
HY-120398
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