1. Metabolic Enzyme/Protease
  2. Farnesyl Transferase
  3. Chaetomellic acid A

Chaetomellic acid A 可从Chaetomella acutiseta中分离出来。Chaetomellic acid A 是法呢基蛋白转移酶的特异性抑制剂。Chaetomellic acid A 可降低氧化应激诱导的细胞凋亡。Chaetomellic acid A 可减轻小鼠单侧输尿管梗阻 (UUO) 后的肾脏损伤。

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Chaetomellic acid A Chemical Structure

Chaetomellic acid A Chemical Structure

CAS No. : 148796-51-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Chaetomellic acid A can be isolated from Chaetomella acutiseta. Chaetomellic acid A is a specific inhibitor of farnesyl-protein transferase. Chaetomellic acid A decreases oxidative stress-induced apoptosis in cells. Chaetomellic acid A reduces renal damage after unilateral ureteral obstruction (UUO) in mice[1][2].

分子量

326.47

Formula

C19H34O4

CAS 号
结构分类
初始来源

Chaetomella acutiseta

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Chaetomellic acid A
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HY-134579
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