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  3. Chitin synthase inhibitor 7

Chitin synthase inhibitor 7 (compound 9c) 是一种有效的 chitin synthase (CHS) 抑制剂,其 IC50 值为 0.37 mM,Chitin synthase inhibitor 7 对耐药真菌具有广谱抗真菌活性。Chitin synthase inhibitor 7 可用于真菌感染的研究。

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Chitin synthase inhibitor 7 Chemical Structure

Chitin synthase inhibitor 7 Chemical Structure

CAS No. : 3033645-30-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Chitin synthase inhibitor 7 (compound 9c) is a potent chitin synthase (CHS) inhibitor with an IC50 value of 0.37 mM. Chitin synthase inhibitor 7 has broad-spectrum antifungal activity against drug-resistant fungi. Chitin synthase inhibitor 7 can be used in the research of fungi infection[1].

体外研究
(In Vitro)

Chitin synthase inhibitor 7 (compound 9c; 300 μg/mL) inhibits chitin synthase (CHS) activity with an inhibition percentage (IP) value of nearly 70% [1].
Chitin synthase inhibitor 7 (1-512 μg/mL) has antifungal activity against four strains with minimum inhibitory concentration (MIC) values of 128, 256, 256, and 256 μg/mL for C. albicans, A. flavus, A. fumigatus, and C. neoformans, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

435.47

Formula

C24H25N3O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Chitin synthase inhibitor 7
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HY-151417
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