2. GPCR/G Protein Neuronal Signaling Autophagy Metabolic Enzyme/Protease
  3. Dopamine Receptor Autophagy Cytochrome P450 5-HT Receptor
  4. Chlorpromazine (hydrochloride) (Standard)

Chlorpromazine (hydrochloride) (Standard)  (Synonyms: 盐酸氯丙嗪 (Standard))

目录号: HY-B0407AR 纯度: ≥98%
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摩尔计算器

Chlorpromazine (hydrochloride) (Standard)是 Chlorpromazine (hydrochloride) 的分析标准品。本产品用于研究及分析应用。Chlorpromazine hydrochloride 是一种口服有效的、可透过血脑屏障的抗精神病剂，能有效拮抗 D2 多巴胺受体和 5-HT2A，已广泛用于精神分裂症和其他精神疾病。Chlorpromazine hydrochloride 可通过多种途径发挥抗癌活性，

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Chlorpromazine (hydrochloride) (Standard) Chemical Structure

Chlorpromazine (hydrochloride) (Standard) Chemical Structure

CAS No. : 69-09-0

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生物活性

Chlorpromazine (hydrochloride) (Standard) is the analytical standard of Chlorpromazine (hydrochloride). This product is intended for research and analytical applications. Chlorpromazine hydrochloride is an orally active, blood-brain barrier-transparent antipsychotic agent that effectively antagonises D2 dopamine receptors and 5-HT2A, which is widely used in schizophrenia and other psychiatric disorders. Chlorpromazine hydrochloride exerts anti-cancer activity through a variety of pathways, including anti-proliferation, induction of autophagy and cycle arrest (G2-M phase), inhibition of cytochrome c oxidase (CcO), inhibition of tumour growth and metastasis, and inhibition of tumour immune escape. Chlorpromazine hydrochloride also blocks hNav1.7 channels (IC50=25.9 μM; concentration-dependent) and HERG potassium channels (IC50=21.6 μM), which has potential for analgesic and cardiac arrhythmic studies. Chlorpromazine hydrochloride also can inhibit clathrin-mediated endocytosis.

分子量

355.33

Formula

C17H20Cl2N2S
CAS 号
中文名称

盐酸氯丙嗪 (Standard)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Chlorpromazine (hydrochloride) (Standard) 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

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Keywords:

Chlorpromazine (hydrochloride) (Standard)69-09-0盐酸氯丙嗪 (Standard)Dopamine ReceptorAutophagyCytochrome P4505-HT ReceptorCYPsSerotonin Receptor5-hydroxytryptamine ReceptoraLQTSU-87MG glioma cellsBone marrow cellscancerschizophreniaCcOtumour immune escapeanalgesiccardiac arrhythmicInhibitorinhibitorinhibit

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