2. Apoptosis
  3. Necroptosis Apoptosis
  4. Cholicamideβ

Cholicamideβ (GMP) 是一种 GMP 级别的 Cholicamideβ。Cholicamideβ (compound 6) 是一种自组装的、小分子、癌症疫苗佐剂。Cholicamideβ 可形成病毒样颗粒，细胞毒性小。Cholicamideβ 与肽抗原结合后，会增强树突状细胞的抗原呈递，并诱导抗原特异性 T 细胞。Cholicamideβ 可诱导细胞凋亡 (apoptosis) 和坏死 (necrosis)。

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Cholicamideβ Chemical Structure

Cholicamideβ Chemical Structure

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Other Forms of Cholicamideβ:

Cholicamideβ 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cholicamideβ (GMP) is a GMP grade of Cholicamideβ. Cholicamideβ (compound 6) is a self-assembling, small molecule, cancer vaccine adjuvant. Cholicamideβ can form virus-like particles with low cytotoxicity. Cholicamideβ, upon binding to peptide antigens, enhances antigen presentation by dendritic cells and induces antigen-specific T cells. Cholicamideβ can induce apoptosis and necrosis[1].

体外研究
(In Vitro)

Cholicamideβ (compound 6) (4-16 μM; 22 h) 在 RAW264.7 细胞中诱导凋亡和坏死[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cholicamideβ 相关抗体:
体内研究
(In Vivo)

Cholicamideβ (compound 6) (100 μg/mouse; 16 h 和 21 d 后检测) 在经由流感裂解疫苗免疫过的 C57BL/6 小鼠中表现出低毒性，增加 HA 特异性 IgG 抗体滴度[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

879.34

Formula

C55H94N2O6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cholicamideβ 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CholicamideβNecroptosisApoptosisApoptosis/Necrosis InducerInhibitorinhibitorinhibit

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