2. Cell Cycle/DNA Damage Stem Cell/Wnt
  3. Casein Kinase
  4. CK2-IN-3

CK2-IN-3 是一种选择性的、有效的 CK2 抑制剂 (Kd: 12 nM), IC50 值为 1.51 μM (CK2α)，7.64 μM (CK2α’)。CK2-IN-3 可用于癌症的研究。

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CK2-IN-3 Chemical Structure

CK2-IN-3 Chemical Structure

CAS No. : 2969205-85-2

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CK2-IN-3 相关抗体

Top Publications Citing Use of Products

查看 Casein Kinase 亚型特异性产品:

查看所有亚型
CK1 CK2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CK2-IN-3 is a selective and potent CK2 inhibitor (Kd: 12 nM), with IC50 values of 1.51 μM (CK2α) and 7.64 μM (CK2α’). CK2-IN-3 can be used in the research of cancers[1].

IC50 & Target[1]

CK2α

1.51 μM (IC50)

CK2α'

7.64 μM (IC50)

体外研究
(In Vitro)

CK2-IN-3 (compound 31, 1 nM-100 μM) inhibits CK2 activities in permeabilized cells, with IC50 values of 8 nM (CK2α) and 38 nM (CK2α’)[1].
CK2-IN-3 (10 µM, 48 h) shows no significant cytotoxicity across 60 cancer cell lines[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CK2-IN-3 相关抗体:
分子量

458.46

Formula

C22H26N4O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CK2-IN-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CK2-IN-32969205-85-2Casein KinaseMacrocyclic kinasepyrimidineNanoBRETantiproliferativecancerInhibitorinhibitorinhibit

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