Clothianidin-d₃  (Synonyms: 噻虫胺-d₃)

Clothianidin-d₃ is the deuterium labeled Clothianidin.Clothianidin-d₃ is a neonicotinoid insecticide. Clothianidin-d₃ shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin-d₃ has various application methods and high safety for crops^[1][2].

Clothianidin-d₃ (30 nM) 在离体神经元上表现出高活性^[3]。
Clothianidin-d₃ (1 µg/L；36 h) 对马利筋中的帝王蝶幼虫显示出亚致死效应^[4]。
Clothianidin-d₃ (0.25 mg/粒 和 0.50 mg/粒) 在玉米和大豆耕作的农田中，在土壤和水中浓度低^[5]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

252.70

C₆H₅D₃ClN₅O₂S

1262776-24-8

210880-92-5

固体

White to off-white

噻虫胺-d₃

Room temperature in continental US; may vary elsewhere.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Uneme H. Chemistry of clothianidin and related compounds. J Agric Food Chem. 2011 Apr 13;59(7):2932-7.  [Content Brief]

  [3]. Nauen R, et al. Thiamethoxam is a neonicotinoid precursor converted to clothianidin in insects and plants[J]. Pesticide biochemistry and physiology, 2003, 76(2): 55-69.

  [4]. Pecenka JR, et al. Non-target effects of clothianidin on monarch butterflies. Naturwissenschaften. 2015 Apr;102(3-4):19.  [Content Brief]

  [5]. de Perre C, et al. Fate and effects of clothianidin in fields using conservation practices. Environ Toxicol Chem. 2015 Feb;34(2):258-65.  [Content Brief]