1. 天然产物
  2. 疾病研究领域 微生物
  3. 癌症
  4. Colistimethate

Colistimethate 是一种多粘菌素,对肾小管细胞有细胞毒性。Colistimethate 在体内无活性。对 6 株铜绿假单胞菌 (P. aeruginosa) 无明显抑制作用。

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Custom Peptide Synthesis

Colistimethate Chemical Structure

Colistimethate Chemical Structure

CAS No. : 12705-41-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Colistimethate is a polymyxin with cytotoxicity to renal tubular cells. Colistimethate has poorly inactive in vivo. Colistimethate shows seldomly detectable activity against 6 strains of P. aeruginosa[1][2].

体外研究
(In Vitro)

Colistimethate is cytotoxic to renal tubular cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Colistimethate is prone to cause nephrotoxicity in vivo[1].
Colistimethate (306 mg/kg; s.c.; single dose) is relatively ineffective against P. aeruginosa strains (i.p.) in mouse[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
分子量

1749.82

Formula

C58H105N16Na5O28S5

CAS 号
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Colistimethate
目录号:
HY-P4067
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