2. Neuronal Signaling Stem Cell/Wnt
  3. γ-secretase
  4. Compound E

Compound E  (Synonyms: γ-Secretase-IN-1)

目录号: HY-14176G
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摩尔计算器

Compound E (GMP) 是 GMP 级别的 Compound E (HY-14176)。GMP 级别的小分子可用做细胞疗法中的辅助试剂。Compound E 是 γ-secretase 抑制剂。 Compound E 抑制 β-amyloid(40)，β-amyloid(42)，和 Notch γ-分泌酶切割的 IC50 值分别为 0.24，0.37，0.32 nM。

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Compound E Chemical Structure

Compound E Chemical Structure

CAS No. : 209986-17-4

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Compound E 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Compound E (GMP) is a GMP-grade Compound E (HY-14176). GMP-grade small molecules can be used as adjuvant reagents in cell therapy. Compound E is a γ-secretase inhibitor. Compound E inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50 values ​​of 0.24, 0.37, and 0.32 nM, respectively[1][2].

分子量

490.50

Formula

C27H24F2N4O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Compound E 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Compound E (GMP)209986-17-4γ-Secretase-IN-1 (GMP)γ-secretaseGamma secretaseInhibitorinhibitorinhibit

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