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CypD-IN-29 (compound 29) 是阿尔兹海默症靶点 CypD 的抑制剂 (KD=88.2 nM),CypD 是线粒体特异性亲环蛋白,可与脑线粒体内 β 淀粉样蛋白结合,促进线粒体通透性过渡孔 (mPTP) 的形成。

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CypD-IN-29 Chemical Structure

CypD-IN-29 Chemical Structure

CAS No. : 1115335-95-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CypD-IN-29 (compound 29) is an inhibitor of the Alzheimer's disease target CypD (KD=88.2 nM). CypD is a mitochondrial-specific cyclophilin that can bind to β-amyloid protein in brain mitochondria and promote the formation of mitochondrial permeability transition pore (mPTP).

分子量

485.53

Formula

C26H20FN5O2S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

CypD-IN-29 相关分类

  • 摩尔计算器

  • 稀释计算器

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产品名称:
CypD-IN-29
目录号:
HY-136804
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