1. Inhibitory Antibodies
  2. Dargistotug

Dargistotug  (Synonyms: M-6223)

目录号: HY-P990031 纯度: 99.36%
COA

Dargistotug (M-6223) 是全人 IgG1 单克隆抗体,靶向 TIGIT(具有 Ig 结构域和 ITIM 的 T 细胞免疫受体)。而 TIGIT 是一种抑制性免疫检查点,通过与 CD155 等抗体结合,促进 NK 细胞耗竭、减少细胞因子的分泌,还可通过直接或间接作用抑制效应 T 细胞、上调 Tregs 细胞的作用,发挥免疫抑制功能。

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CAS No. : 2649362-29-6

1.  客户无需承担相应的运输费用。

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
1 mg ¥3500
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5 mg ¥9100
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dargistotug (M-6223) is a fully human IgG1 monoclonal antibody targeting TIGIT (T cell immune receptor with Ig domain and ITIM). TIGIT is an inhibitory immune checkpoint that promotes NK cell depletion and reduces the secretion of cytokines by binding to CD155 and other antibodies. It can also directly or indirectly inhibit effector T cells and upregulate Tregs cells, thereby exerting immunosuppression. Function[1].

同型

Human IgG1 kappa

推荐同型对照抗体
种属

Human

CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG1 kappa
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Dargistotug
目录号:
HY-P990031
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