1. Protein Tyrosine Kinase/RTK
  2. Bcr-Abl
  3. Dasatinib intermediate-1

Dasatinib intermediate-1 是 Dasatinib (HY-10181) 合成的中间体。Dasatinib 是一种具有口服活性的,ATP 竞争性的,双重 Src/Bcr-Abl 抑制剂,具有有效的抗肿瘤活性。

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Dasatinib intermediate-1 Chemical Structure

Dasatinib intermediate-1 Chemical Structure

CAS No. : 302964-08-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dasatinib intermediate-1 is an intermediate in the synthesis of Dasatinib (HY-10181). Dasatinib Is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity[1].

分子量

394.28

Formula

C16H13Cl2N5OS

CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

Dasatinib intermediate-1 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Dasatinib intermediate-1
目录号:
HY-41940
需求量: