1. Epigenetics
  2. Epigenetic Reader Domain
  3. DCSM06

DCSM06 是 SWI/SNF 染色质重塑复合物 SMARCA2 的溴结构域抑制剂,IC50 为 9.7 μM。

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DCSM06 Chemical Structure

DCSM06 Chemical Structure

CAS No. : 924855-67-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DCSM06 is an inhibitor for the bromodomain of SWI/SNF chromatin remodeling complexe SMARCA2 with an IC50 of 9.7 μM[1]

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HGC-27 IC50
4.22 μM
Compound: 46
Cytotoxicity against human HGC27 cells assessed as reduction in cell viability after 72 hrs by Alamar blue assay
Cytotoxicity against human HGC27 cells assessed as reduction in cell viability after 72 hrs by Alamar blue assay
[PMID: 30128079]
分子量

324.46

Formula

C21H28N2O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
DCSM06
目录号:
HY-161888
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