2. Anti-infection
  3. Dengue virus Flavivirus Virus Protease
  4. DENV-IN-9

DENV-IN-9 (Compound 5f) 是一种 DENV2 抑制剂，EC50 为 0.88 μM。

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DENV-IN-9 Chemical Structure

DENV-IN-9 Chemical Structure

CAS No. : 791838-63-6

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DENV-IN-9 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DENV-IN-9 (Compound 5f) is a DENV2 inhibitor with an EC50 of 0.88 μM[1].

IC50 & Target

EC50: 0.88 μM (DENV2)[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
KB IC50
14.1 μM
Compound: 25
Inhibitory activity against KB cell line after 72 h of drug exposure
Inhibitory activity against KB cell line after 72 h of drug exposure
[PMID: 15481991]
KB 3-1 IC50
18.7 μM
Compound: 25
Inhibitory activity against KB/MDR cell line after 72 hr of drug exposure
Inhibitory activity against KB/MDR cell line after 72 hr of drug exposure
[PMID: 15481991]
体外研究
(In Vitro)

DENV-IN-9 (Compound 5f) (72 h) 对 DENV2 感染的 LLC/MK2 细胞具有抗登革热活性，EC50 为 0.88 ± 0.14 μM，对正常细胞具有低毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

DENV-IN-9 相关抗体:
分子量

349.13

Formula

C15H9BrO5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DENV-IN-9 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DENV-IN-9791838-63-6Dengue virusFlavivirusVirus ProteaseDENVDENV2LLC/MK2anti-dengueInhibitorinhibitorinhibit

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目录号：
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