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Deoxyharringtonine 是一种从 Cephalotaxus genus 中分离得到的具有显着抗白血病活性的生物碱。

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Deoxyharringtonine Chemical Structure

Deoxyharringtonine Chemical Structure

CAS No. : 36804-95-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Deoxyharringtonine is an alkaloid isolated from Cephalotaxus genus with significant anti-leukemic activity[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HL-60 IC50
0.02 μM
Compound: Deoxyharringtonine
Cytotoxicity against human HL60 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay
Cytotoxicity against human HL60 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay
10.1039/C0MD00241K
体外研究
(In Vitro)

Deoxyharringtonine 作用于 P388 白血病细胞的 IC50 值为 7.5 ng/mL。此外,其对造血细胞系如 HL-60、HL-60/RV+、JURKAT、ALL3、NCEB1、JEKO、MOLT-3 等具有极强的细胞毒活性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

515.60

Formula

C28H37NO8

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Deoxyharringtonine 相关分类

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Deoxyharringtonine
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HY-133900
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