2. Anti-infection
  3. Bacterial
  4. Desotamide

Desotamide 是一种环状六肽抗生素，最初从链霉菌中分离出来。它对金黄色葡萄球菌、肺炎链球菌和耐甲氧西林表皮葡萄球菌 (MRSE；MIC 分别为 16、12.5 和 32 μg/mL) 有效。

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Custom Peptide Synthesis

Desotamide Chemical Structure

Desotamide Chemical Structure

CAS No. : 194660-14-5

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Desotamide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Desotamide is a cyclic hexapeptide antibiotic originally isolated from Streptomyces. It is active against S. aureus, S. pneumoniae, and methicillin-resistant S. epidermidis (MRSE; MICs=16, 12.5, and 32 μg/mL, respectively).

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 IC50
> 100 μM
Compound: 1
Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
[PMID: 25072108]
MCF7 IC50
> 100 μM
Compound: 1
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
[PMID: 25072108]
NCI-H460 IC50
> 100 μM
Compound: 1
Cytotoxicity against human NCI-H460 after 72 hrs by SRB assay
Cytotoxicity against human NCI-H460 after 72 hrs by SRB assay
[PMID: 25072108]
SF-268 IC50
> 100 μM
Compound: 1
Cytotoxicity against human SF268 cells after 72 hrs by SRB assay
Cytotoxicity against human SF268 cells after 72 hrs by SRB assay
[PMID: 25072108]
分子量

696.84

Formula

C35H52N8O7
CAS 号
Sequence

cyclo(Asn-Gly-Trp-Leu-Leu-Ile)
Sequence Shortening

cyclo(NGWLLI)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Desotamide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Desotamide194660-14-5Desotamide ABacterialInhibitorinhibitorinhibit

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目录号：
HY-P3119
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