1. Vitamin D Related/Nuclear Receptor
  2. Progesterone Receptor
  3. Dexamethasone oxetanone

Dexamethasone oxetanone  (Synonyms: Dex-Ox)

目录号: HY-147220
产品使用指南

Dexamethasone oxetanone (Dex-Ox) 是糖皮质激素选择性类固醇地塞米松 (Dex) 的衍生物,是一种抗糖皮质激素。Dexamethasone oxetanone 是一种抗孕激素,具有显着的孕酮受体 (PR) A 和 B 异构体激动剂活性。

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Dexamethasone oxetanone Chemical Structure

Dexamethasone oxetanone Chemical Structure

CAS No. : 4089-36-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dexamethasone oxetanone (Dex-Ox), a derivative of the glucocorticoid-selective steroid Dexamethasone (Dex), is an antiglucocorticoid. Dexamethasone oxetanone is an antiprogestin with significant agonist activity with progesterone receptor (PR) A and B isoforms[1][2].

体外研究
(In Vitro)

Dexamethasone oxetanone (1 μM) exhibits significant quantities of agonist activity with transfected PR in CV-1 cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

374.45

Formula

C22H27FO4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Dexamethasone oxetanone
目录号:
HY-147220
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