1. Immunology/Inflammation
  2. STING
  3. diABZI-4

diABZI-4 是一种具有口服活性的 STING 激动剂,具有广谱抗病毒活性。diABZI-4 通过激活 STING 来诱导促炎细胞因子的产生和淋巴细胞的激活,从而抑制 A 型流感病毒 (IAV)、SARS-CoV-2 和人类鼻病毒 (HRV) 的复制,EC50 的范围为 11.8-199 nM。

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diABZI-4 Chemical Structure

diABZI-4 Chemical Structure

CAS No. : 2138299-65-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

diABZI-4 is an oral active STING agonist with broad-spectrum antiviral activity. diABZI-4 induces the production of pro-inflammatory cytokines and lymphocyte activation by activating STING, thereby inhibiting the replication of influenza A virus (IAV), SARS-CoV-2, and human rhinovirus (HRV), with an EC50 range of 11.8-199 nM[1][2].

分子量

880.82

Formula

C40H51Cl2N13O6

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
diABZI-4
目录号:
HY-168034
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