2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. Dideoxycytidinene

Dideoxycytidinene  (Synonyms: 2′,3′-Didehydro-2′,3′-dideoxycytidine)

目录号: HY-145791
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摩尔计算器

Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。

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Dideoxycytidinene Chemical Structure

Dideoxycytidinene Chemical Structure

CAS No. : 7481-88-1

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Other Forms of Dideoxycytidinene:

Dideoxycytidinene 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

Dideoxycytidinene (2′,3′-Didehydro-2′,3′-dideoxycytidine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 ED50
10 nM
Compound: 1
Concentration required to inhibit 50% of extracellular circular replication of HBV DNA using 2215 cell line
Concentration required to inhibit 50% of extracellular circular replication of HBV DNA using 2215 cell line
[PMID: 8627596]
HepG2 ED50
8 nM
Compound: 1
Concentration required to inhibit 50% of intracellular circular replication of HBV DNA using 2215 cell line
Concentration required to inhibit 50% of intracellular circular replication of HBV DNA using 2215 cell line
[PMID: 8627596]
分子量

209.20

Formula

C9H11N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dideoxycytidinene 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Dideoxycytidinene7481-88-12′,3′-Didehydro-2′,3′-dideoxycytidineNucleoside Antimetabolite/Analogindolent lymphoid malignanciesantitumorInhibitorinhibitorinhibit

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