2. Metabolic Enzyme/Protease NF-κB Immunology/Inflammation Neuronal Signaling
  3. Endogenous Metabolite Reactive Oxygen Species α-synuclein
  4. Dopal

Dopal 是一种醛，在帕金森病中可通过多巴胺的酶促降解产生。Dopal 可产生活性氧，并引发 α-突触核蛋白的聚集。多巴胺可引发 α-突触核蛋白的积累并阻碍原代神经元中 α-突触核蛋白的清除。

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Dopal Chemical Structure

Dopal Chemical Structure

CAS No. : 5707-55-1

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Dopal 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dopal is an aldehyde that can be generated in Parkinson's disease by enzymatic degradation of dopamine. Dopal can generate reactive oxygen species, and triggers aggregation of α-synuclein. DOPAL elicits α-synuclein accumulation and hampers α-synuclein clearance in primary neurons[1][2].

分子量

152.15

Formula

C8H8O3
CAS 号
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dopal 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Dopal5707-55-1Endogenous MetaboliteReactive Oxygen Speciesα-synucleinα-SynneuronPDParkinson'sInhibitorinhibitorinhibit

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