DPC-AJ1951 TFA 

DPC-AJ1951 TFA, a 14 amino acid peptide that acts as a potent agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). And characterized the activity of DPC-AJ1951 TFA in ex vivo and in vivo assays of bone resorption^[1].

DPC-AJ1951 TFA induces intracellular Ca²⁺ mobilization in HEK 293 cells transfected with the human PPR (EC₅₀ 26±14 nM)^[1][1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

1666.99 (free base)

C₇₆H₁₂₇N₂₃O₁₉.xC₂HF₃O₂

固体

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{Aib}-Val-{Aib}-Glu-Ile-Gln-Leu-{Nle}-His-Gln-Arg-Ala-Lys-Tyr-NH2

{Aib}V{Aib}EIQL{Nle}HQRAKY-NH2

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

• [1]. Percy H Carter, et al. Discovery of a Small Molecule Antagonist of the Parathyroid Hormone Receptor by Using an N-terminal Parathyroid Hormone Peptide Probe. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6846-51.  [Content Brief]