2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. DR4485 hydrochloride

DR4485 (hydrochloride) 是一种具有口服活性和选择性的 5-HT7 拮抗剂(pKi=8.14)。

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DR4485 hydrochloride Chemical Structure

DR4485 hydrochloride Chemical Structure

CAS No. : 402942-53-4

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规格 价格 是否有货 数量
5 mg ￥4635
3 - 4 周
10 mg 现货 3 - 4 周
50 mg   询价  
100 mg   询价  

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Customer Review

DR4485 hydrochloride 相关抗体

Top Publications Citing Use of Products

查看 5-HT Receptor 亚型特异性产品:

查看所有亚型
5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DR4485 (hydrochloride) is an orally active and selective 5-HT7 antagonist (pKi=8.14)[1].

IC50 & Target[1]

5-HT7 Receptor

8.14 (pKi)

体外研究
(In Vitro)

DR4485 (MZ54 WT cells; 6 µM or 8 µM) hydrochloride induces autophagy as well as cell death that is diminished by KO of ATG5 and ATG7[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

DR4485 hydrochloride 相关抗体:
分子量

491.88

Formula

C26H29Cl3N2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DR4485 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DR4485402942-53-4DR 4485DR-44855-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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产品名称：
DR4485 hydrochloride
目录号：
HY-103126
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