2. Metabolic Enzyme/Protease
  3. Dipeptidyl Peptidase
  4. Dutogliptin tartrate

Dutogliptin tartrate  (Synonyms: PHX-1149)

目录号: HY-10286A
产品使用指南

摩尔计算器

Dutogliptin tartrate (PHX-1149) 是一种口服有效的选择性二肽基肽酶-4 (DPP4) 抑制剂，可用于 2 型糖尿病的研究。

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Dutogliptin tartrate Chemical Structure

Dutogliptin tartrate Chemical Structure

CAS No. : 890402-81-0

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Dutogliptin tartrate 的其他形式现货产品:

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Dutogliptin tartrate 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dutogliptin tartrate (PHX-1149) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.

IC50 & Target

DPP4[1]
体内研究
(In Vivo)

Dutogliptin exhibits low plasma protein binding (11%) and is rapidly absorbed with a Tmax of 3-4 h and a half-life of 10-13 h. Dutogliptin is metabolically stable and does not inhibit or induce the activity of major CYP450s[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

391.18

Formula

C14H26BN3O9
CAS 号
中文名称

杜拓格利普汀酒石酸盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dutogliptin tartrate 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dutogliptin890402-81-0PHX-1149杜拓格利普汀酒石酸盐PHX1149PHX 1149Dipeptidyl PeptidaseDPPDPP4diabetesmellitusInhibitorinhibitorinhibit

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