2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. (E)-3-AP

(E)-3-AP  (Synonyms: (E)-PAN-811; (E)-NSC# 663249; (E)-OCX191)

目录号: HY-10082A
产品使用指南

摩尔计算器

(E)-3-AP 是 3-AP 的E 构型。3-AP 是一种有效的 核糖核苷酸还原酶 抑制剂。3-AP 显示出抗增殖活性。3-AP 在 L1210 白血病模型中显示出抗癌活性。3-AP 抑制 RR 活性和 DNA 合成。

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(E)-3-AP Chemical Structure

(E)-3-AP Chemical Structure

CAS No. : 200933-27-3

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规格 是否有货
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Customer Review

Other Forms of (E)-3-AP:

(E)-3-AP 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(E)-3-AP is the E configuration of 3-AP. 3-AP is a potent ribonucleotide reductase inhibitor. 3-AP shows anti-proliferative activity. 3-AP shows anticancer activity in L1210 leukemia model. 3-AP inhibits RR activity and DNA synthesis[1][2].

体外研究
(In Vitro)

3-AP shows anti-proliferative activity with IC50 values of 1.3, 1.6 µM for L1210, L1210/HUr cells, respectively[1].
3-AP (5, 10, 15, 20, 30 mg/kg; i.p.; twice daily for six consecutive days) significantly increases in life span were observed with each dosage employed and long term survivors[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(E)-3-AP 相关抗体:
分子量

195.24

Formula

C7H9N5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(E)-3-AP 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(E)-3-AP200933-27-3(E)-PAN-811 (E)-NSC# 663249 (E)-OCX191DNA/RNA SynthesisL1210 leukemia cellsanti-proliferativeanticancerDNA synthesisInhibitorinhibitorinhibit

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