2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. (S,R,S)-AHPC-C10-NH2

(S,R,S)-AHPC-C10-NH2  (Synonyms: VH032-C10-NH2)

目录号: HY-129941
产品使用指南

摩尔计算器

(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) 是一种合成的 E3 连接酶配体-linker 偶联物 (E3 ligase ligand-linker conjugate)，包含基于 (S,R,S)-AHPC 的 VHL 配体和 1 个 linker。用于合成 BET 的靶向 PROTAC。

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(S,R,S)-AHPC-C10-NH2 Chemical Structure

(S,R,S)-AHPC-C10-NH2 Chemical Structure

CAS No. : 2341796-74-3

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Other Forms of (S,R,S)-AHPC-C10-NH2:

(S,R,S)-AHPC-C10-NH2 相关抗体

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查看 E3 Ligase Ligand-Linker Conjugates 亚型特异性产品:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for BET-Targeted PROTAC[1].

IC50 & Target[1]

VHL

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(S,R,S)-AHPC-C10-NH2 相关抗体:
分子量

613.85

Formula

C33H51N5O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(S,R,S)-AHPC-C10-NH2 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S,R,S)-AHPC-C10-NH22341796-74-3VH032-C10-NH2E3 Ligase Ligand-Linker ConjugatesPROTACAHPCVHLBETInhibitorinhibitorinhibit

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